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| Name | Indication | Economics | Approved | Competition | Administration | Mechanism | IP | | Price | 25.77 | |
| Risperdal Consta | Schizophrenia | 2.5%, JNJ | 10/29/2003 | Invega Sustenna | IM q2w | Atypical | Medisorb, 10-17 | | Shares | 164.254275 | Q222 |
| Vivitrol | Alcoholism | 1 | 4/1/2006 | Campral, Oral Naltrexone | IM qm | Naltrexone | Medisorb, 10-17 | | MC | 4232.8326667500005 | |
| | | | Phase | | | | | | Cash | 759.977 | Q222 |
| Byetta LAR | T2 diabetes | AMLN | | Lariglutide, Januvia | IM qw | GLP1 | Medisorb, 10-17, Biologic | | Debt | 294.537 | Q222 |
| | | | | | | | | | EV | 3767.3926667500004 | |
| ALKS 33 | Addiction | 1 | I | | Oral | Opioid Receptor | | | | | |
| ALKS 29 | Alcohol dependence | 1 | I | | Oral | Baclofen/ALKS33 | | | | | |
| nemvaleukin alfa | Mucosal Melanoma | 1 | | | | | | | | | |
| ALKS 36 | Pain | 1 | I | | Oral | | | | Jessica Rege, VP, Head of Oncology | | |
| ALKS 27 | COPD | 1 | N/A | Spiriva | Inhaled | trospium | | | | | |
| ALKS 37 | OIC | 1 | I | Entereg, Relistor | Oral | Opioid Antagonist | | | | | |
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| 1. Can agreement with JNJ be re-negotiated? Does the current agreement preclude an acquisition of Alkermes? Has JNJ violated the agreement by developing Sustenna? | | | | | | | | | | | |
| 2. Can the Alkermes technology be added to other pharmaceutical products? Antipsychotics? Antidiabetics? HIV? Alzheimer's? Parkinsons? Pain? Bisphosphonates? Others? Compliance sensitive, smaller molecule. | | | | | | YE09? - Vivitrol in opiate dependence Phase III | | | | | |
| 3. Will Vivitrol succeed in opioid addiction study? Can the product be meaningful regardless? | | | | | | YE09? - Victoza FDA action | | | | | |
| 4. Pipeline: ALKS33: Is doing a phase 2 head-to-head versus naltrexone worth the expense? | | | | | | Q1 2010: Byetta LAR DURATION-4 results. | | | | | |
| 5. Longevity of Risperdal Consta. Liability to succumb to Invega Sustenna competition. | | | | | | March 2010: Byetta LAR PDUFA. | | | | | |
| 6. Sales potential of Byetta LAR | | | | | | 1H10: JNJ files Sustenna in Europe. | | | | | |
| 7. IP of Medisorb, difficulty in genericizing. | | | | | | | | | | | |
| 8. Budgeting core expenses - $3.1m annual lease expense. 570 FTEs. | | | | | | | | | | | |