ABCDEFGHIJ
1Main
2BrandGenericIndicationMOAApprovedEconomics
3Ariceptdonepezil4523, PFE
4rivastigmine
5memantine
6Aduhelm, fka BIIB037aducanumabpolymeric abeta abBIIB/4523/NeurimmunenoN-terminal
7galantamine
8BrandGenericIndicationMOAPhaseEconomicsLast Trial DateMonomer?Epitope
9LY3002813donanemabN3pG abeta abIII ongoingLLY
10BAN2401lecanemabCDR=0.5-1.0, MMSE>=22amyloid beta antibodyIII completedBIIB, 4523, BioArctic3/25/2019no
11AAB-001bapineuzumabN-terminal abeta abIII completedELN, PFE/WYE, JNJ12/17/2007yesN-terminal
12LY2062430solanezumabsoluble abeta abLLYyes16-26
13RG7412, MABT5102Acrenezumababeta abROG13-24
14RO4909832gantenerumababeta abROG3-11, 18-27
15SAR228810polymer abeta abSNY
16ponezumabPfizer (Rinat)30-40
17LY3372993remternetugN3pG abeta ab?LLY
18LY3372689O-GlcNAcase inhibitorLLY
19LY3303560zagotenemabtau mabLLY
20LY3154207mevidalenD1 pamLLY
21RVT-001intepirdine
22DimebonMDVN
23azeliragon
24Lu AE58054idalopirdine
25IGIV
26CNP520umibecestatBACE1 inhibitorNVS, AMGN
27LY3202626BACE inhibitorLLY
28LY3314814lanabecestatBACE inhibitorLLY
29E2609elenbecestatBACE inhibitor4523 JP
30atabecestatBACE inhibitorJNJ
31MK-8931verubecestatBACE1 inhibitorMRK
32LY405139semagacestatgamma secretaseLLY
33ANAVEX2-73
34simufilam
35UCB0107bepranemab
36semorinemab
37BIIB080
38E2814
39IONIS-MAPTRx
40RO7126209
41JNJ-63733657
42JNJ-54861911TauII
43ABBV-8E12
44ABBV-916
45AL002
46ACI-35.030
47JACI-35.054
48ACI-24.060
49BI 425809
50BI 409306
51CAD106