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311: Hill AM. Alzheimer disease and the evolving treatment landscape. Am J Manag Care. 2022 Sep;28(10 Suppl):S179-S187. doi: 10.37765/ajmc.2022.89235. PMID:36197131
452: Tian Y, Viles JH. pH Dependence of Amyloid-β Fibril Assembly Kinetics: Unravelling the Microscopic Molecular Processes. Angew Chem Int Ed Engl. 2022 Oct 5. doi: 10.1002/anie.202210675. Epub ahead of print. PMID: 36197009.
543: Cisternas P, Taylor X, Martinez P, Maldonado O, Jury N, Lasagna-Reeves CA. The reduction of astrocytic tau prevents amyloid-β-induced synaptotoxicity. Brain Commun. 2022 Sep 19;4(5):fcac235. doi: 10.1093/braincomms/fcac235. PMID:36196088; PMCID: PMC9527666.
614: Kang SH, Lee KH, Chang Y, Choe YS, Kim JP, Jang H, Shin HY, Kim HJ, Koh SB,Na DL, Seo SW, Kang M. Gender-specific relationship between thigh muscle and fat mass and brain amyloid-β positivity. Alzheimers Res Ther. 2022 Oct 4;14(1):145.doi: 10.1186/s13195-022-01086-5. PMID: 36195949.
715: Xu L, Li M, Wei A, Yang M, Li C, Liu R, Zheng Y, Chen Y, Wang Z, Wang K, WangT. Treadmill exercise promotes E3 ubiquitin ligase to remove amyloid β and P-tau and improve cognitive ability in APP/PS1 transgenic mice. J Neuroinflammation.2022 Oct 4;19(1):243. doi: 10.1186/s12974-022-02607-7. PMID: 36195875.
816: An F, Zhao R, Xuan X, Xuan T, Zhang G, Wei C. Calycosin ameliorates advanced glycation end product-induced neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer's disease. Chem Biol Interact. 2022 Oct1:110206. doi: 10.1016/j.cbi.2022.110206. Epub ahead of print. PMID: 36195188.
927: Zhang X, Kang X, Du L, Zhang L, Huang Y, Wang J, Wang S, Chang Y, Liu Y, Zhao Y. Tanshinone IIA loaded chitosan nanoparticles decrease toxicity of β-amyloidpeptide in a Caenorhabditis elegans model of Alzheimer's disease. Free RadicBiol Med. 2022 Oct 1:S0891-5849(22)00620-7. doi:
1058: Henríquez G, Méndez L, Castañeda E, Wagler A, Jeon S, Narayan M. Preclinical Model to Evaluate Outcomes of Amyloid Cross-Toxicity in the Rodent Brain. ACSChem Neurosci. 2022 Oct 4. doi: 10.1021/acschemneuro.2c00419. Epub ahead ofprint. PMID: 36194532.
1129: Eo H, Lee S, Kim SH, Ju IG, Huh E, Lim J, Park S, Oh MS. <i>Petasites japonicus</i> leaf extract inhibits Alzheimer's-like pathology through suppression of neuroinflammation. Food Funct. 2022 Oct 4. doi:10.1039/d2fo01989b. Epub ahead of print. PMID: 36193798.
12210: Svenningsson AL, Stomrud E, Palmqvist S, Hansson O, Ossenkoppele R. Axonal degeneration and amyloid pathology predict cognitive decline beyond cortical atrophy. Alzheimers Res Ther. 2022 Oct 4;14(1):144. doi:10.1186/s13195-022-01081-w. PMID: 36192766.
13311: Wouters Y, Jaspers T, Rué L, Serneels L, De Strooper B, Dewilde M. VHHs as tools for therapeutic protein delivery to the central nervous system. Fluids Barriers CNS. 2022 Oct 3;19(1):79. doi: 10.1186/s12987-022-00374-4. PMID:36192747
14312: Nakajima K, Yamaguchi K, Noji M, Aguirre C, Ikenaka K, Mochizuki H, Zhou L, Ogi H, Ito T, Narita I, Gejyo F, Naiki H, Yamamoto S, Goto Y. Macromolecular crowding and supersaturation protect hemodialysis patients from the onset of dialysis-related amyloidosis. Nat Commun. 2022 Oct 3;13(1):5689. doi:10.1038/s41467-022-33247-3. PMID: 36192385.
15213: Cheung CY, Ran AR, Wang S, Chan VTT, Sham K, Hilal S, Venketasubramanian N, Cheng CY, Sabanayagam C, Tham YC, Schmetterer L, McKay GJ, Williams MA, Wong A, Au LWC, Lu Z, Yam JC, Tham CC, Chen JJ, Dumitrascu OM, Heng PA, Kwok TCY, Mok VCT, Milea D, Chen CL, Wong TY. A deep learning model for detection of Alzheimer's disease based on retinal photographs: a retrospective, multicentrecase-control study. Lancet Digit Health. 2022 Sep 30:S2589-7500(22)00169-8. doi:10.1016/S2589-7500(22)00169-8. Epub ahead of print. PMID: 36192349.
16214: Parent JH, Ciampa CJ, Harrison TM, Adams JN, Zhuang K, Betts MJ, Maass A, Winer JR, Jagust WJ, Berry AS. Locus coeruleus catecholamines link neuroticism and vulnerability to tau pathology in aging. Neuroimage. 2022 Sep 30:119658.doi: 10.1016/j.neuroimage.2022.119658. Epub ahead of print. PMID: 36191755.
17415: Huang Y, Lemke G. Early death in a mouse model of Alzheimer's disease exacerbated by microglial loss of TAM receptor signaling. Proc Natl Acad Sci U SA. 2022 Oct 11;119(41):e2204306119. doi: 10.1073/pnas.2204306119. Epub 2022 Oct3. PMID: 36191221.
18316: Huber CC, Callegari EA, Paez MD, Romanova S, Wang H. Heat Shock-Induced Extracellular Vesicles Derived from Neural Stem Cells Confer Marked Neuroprotection Against Oxidative Stress and Amyloid-β-Caused Neurotoxicity. Mol Neurobiol. 2022 Oct 3. doi: 10.1007/s12035-022-03055-3. Epub ahead of print.PMID: 36190693.
19517: Xiong Y, Izadi S, Onufriev AV. Fast Polarizable Water Model for Atomistic Simulations. J Chem Theory Comput. 2022 Oct 3. doi: 10.1021/acs.jctc.2c00378.Epub ahead of print. PMID: 36190318.
20318: Xu H, Zhao Y, Qi Y, Xue X, Liu Y. Therapeutic nanosweepers promote β-amyloid removal from the brain for Alzheimer's disease treatment. Biomater Sci. 2022 Oct3. doi: 10.1039/d2bm01319c. Epub ahead of print. PMID: 36190131.
21319: Liu Y, Zhuang D, Wang J, Huang H, Li R, Wu C, Deng Y, Hu G, Guo B. Recent advances in small molecular near-infrared fluorescence probes for a targeted diagnosis of the Alzheimer disease. Analyst. 2022 Oct 3. doi:10.1039/d2an01327d. Epub ahead of print. PMID: 36190126.
22520: Tanaka K, Kuramoto K, Nakagawa T, Nomura Y, Ozawa K, Hosoi T. C-terminal fragment of APP interacts with p62, forms an aggregate, and induces autophagic degradation in Alzheimer's cell model. Am J Physiol Cell Physiol. 2022 Oct 3.doi: 10.1152/ajpcell.00003.2022. Epub ahead of print. PMID: 36189972.
23121: Shepherd-Banigan ME, Ford CB, Smith VA, Belanger E, Wetle TT, Plassman BL, Burke JR, DePasquale N, O'Brien EC, Sorenson C, Van Houtven CH. Amyloid-β PET Scan Results Disclosure and Care-Partner Emotional Well-Being Over Time. J Alzheimers Dis. 2022 Sep 30. doi: 10.3233/JAD-220611. Epub ahead of print. PMID:36189596
24522: Yang YH, Hsieh SW, Chang HW, Sung JL, Chuu CP, Yen CW, Hour TC. Gamma Frequency Inhibits the Secretion and Aggregation of Amyloid-β and Decreases the Phosphorylation of mTOR and Tau Proteins in vitro. J Alzheimers Dis. 2022 Sep28. doi: 10.3233/JAD-220307. Epub ahead of print. PMID: 36189589.
25223: Hori Y, Sohma Y, Kanai M, Tomita T. Promotion in the Clearance of Aggregated Aβ In Vivo Using Amyloid Selective Photo-Oxygenation Technology. Neurosci Insights. 2022 Sep 28;17:26331055221126179. doi: 10.1177/26331055221126179.PMID: 36189373; PMCID: PMC9523840.
26124: Li W, Li R, Wang Y, Zhang Y, Tomar MS, Dai S. Calcitonin gene-related peptide is a potential autoantigen for CD4 T cells in type 1 diabetes. Front Immunol. 2022 Sep 16;13:951281. doi: 10.3389/fimmu.2022.951281. PMID: 36189304;PMCID: PMC9523785.
27225: Mello-Carpes PB, Inestrosa NC, Paula-Lima AC. Editorial: Molecular mechanisms of Alzheimer's disease: From top to bottom. Front Aging. 2022 Sep16;3:1026942. doi: 10.3389/fragi.2022.1026942. PMID: 36187848; PMCID:PMC9523882.
28326: Hu S, Wan X, Li X, Wang X. Aerobic exercise alleviates pyroptosis-related diseases by regulating NLRP3 inflammasome. Front Physiol. 2022 Sep 15;13:965366.doi: 10.3389/fphys.2022.965366. PMID: 36187801; PMCID: PMC9520335.
29227: Garcia J, Chang R, Steinberg RA, Arce A, Yang J, Van Der Eb P, Abdullah T, Chandrashekar DV, Eck SM, Meza P, Liu ZX, Cadenas E, Cribbs DH, Kaplowitz N, Sumbria RK, Han D. Modulation of hepatic amyloid precursor protein and lipoprotein receptor-related protein 1 by chronic alcohol intake: Potential link between liver steatosis and amyloid-β. Front Physiol. 2022 Sep 15;13:930402.doi: 10.3389/fphys.2022.930402. PMID: 36187787; PMCID: PMC9520570.
30528: Nazere K, Takahashi T, Hara N, Muguruma K, Nakamori M, Yamazaki Y, Morino H, Maruyama H. Amyloid Beta Is Internalized <i>via</i> Macropinocytosis, an HSPG-and Lipid Raft-Dependent and Rac1-Mediated Process. Front Mol Neurosci. 2022 Feb11;15:804702. doi: 10.3389/fnmol.2022.804702. PMID: 36187354; PMCID: PMC9524458.
31329: Lourenco MV, de Freitas GB, Raony Í, Ferreira ST, De Felice FG. Irisin stimulates protective signaling pathways in rat hippocampal neurons. Front Cell Neurosci. 2022 Sep 9;16:953991. doi: 10.3389/fncel.2022.953991. PMID: 36187295;PMCID: PMC9518673.
32230: Hung SM, Wu DA, Shimojo S, Arakaki X. Stronger implicit interference in cognitively healthy older participants with higher risk of Alzheimer's disease. Alzheimers Dement (Amst). 2022 Sep 20;14(1):e12340. doi: 10.1002/dad2.12340.PMID: 36187196; PMCID: PMC9489163.
33531: Luo Z, Wang Y, Pang S, Gao S, Liu N, Gao X, Zhang L, Qi X, Yang Y, Zhang L. Synthesis and Bioactivity Evaluation of a Novel 1,2,4-Oxadiazole Derivative in vitro and in 3×Tg Mice. Drug Des Devel Ther. 2022 Sep 25;16:3285-3296. doi:10.2147/DDDT.S372750. PMID: 36187086; PMCID: PMC9521684.
34232: Gallucci M, Grassivaro F, Da Ronch C, Fiore V, Bonifati DM, Bendini M, Zanusso G, Bonanni L. Patient with Corticobasal Syndrome Showing Disease-Associated Biomarkers of Dementia with Lewy Bodies: A Treviso Dementia (TREDEM) Registry Case Report. J Alzheimers Dis Rep. 2022 Aug 1;6(1):431-442. doi:10.3233/ADR-220026. PMID: 36186723; PMCID: PMC9484149.
35533: Hong M, Kim M, Yoon J, Lee SH, Baik MH, Lim MH. Excited-State Intramolecular Hydrogen Transfer of Compact Molecules Controls Amyloid Aggregation Profiles. JACS Au. 2022 Aug 11;2(9):2001-2012. doi: 10.1021/jacsau.2c00281. PMID:36186552; PMCID: PMC9516708.
36334: Wang T, Chen Y, Zou Y, Pang Y, He X, Chen Y, Liu Y, Feng W, Zhang Y, Li Q, Shi J, Ding F, Marshall C, Gao J, Xiao M. Locomotor Hyperactivity in the Early-Stage Alzheimer's Disease-like Pathology of APP/PS1 Mice: Associated with Impaired Polarization of Astrocyte Aquaporin 4. Aging Dis. 2022 Oct1;13(5):1504-1522. doi: 10.14336/AD.2022.0219. PMID: 36186142; PMCID: PMC9466968.
37335: Tao QQ, Lin RR, Chen YH, Wu ZY. Discerning the Role of Blood Brain Barrier Dysfunction in Alzheimer's Disease. Aging Dis. 2022 Oct 1;13(5):1391-1404. doi:10.14336/AD.2022.0130-1. PMID: 36186141; PMCID: PMC9466977.
38536: Tomassen J, den Braber A, van der Landen SM, Konijnenberg E, Teunissen CE, Vermunt L, de Geus EJC, Boomsma DI, Scheltens P, Tijms BM, Visser PJ. Abnormal cerebrospinal fluid levels of amyloid and tau are associated with cognitive decline over time in cognitively normal older adults: A monozygotic twin study. Alzheimers Dement (N Y). 2022 Sep 20;8(1):e12346. doi: 10.1002/trc2.12346. PMID:36185992; PMCID: PMC9489168.
39237: Liu N, Liang X, Yang C, Hu S, Luo Q, Luo H. Dual-targeted magnetic mesoporous silica nanoparticles reduce brain amyloid-β burden via depolymerization and intestinal metabolism. Theranostics. 2022 Sep11;12(15):6646-6664. doi: 10.7150/thno.76574. PMID: 36185606; PMCID: PMC9516238.
40138: Pan H, Cao J, Wu C, Huang F, Wu P, Lang J, Liu Y. Osteoporosis is associated with elevated baseline cerebrospinal fluid biomarkers and accelerated brain structural atrophy among older people. Front Aging Neurosci. 2022 Sep16;14:958050. doi: 10.3389/fnagi.2022.958050. PMID: 36185490; PMCID: PMC9523506.
41139: Wang CC, Kong JY, Li XY, Yang JY, Xue CH, Yanagita T, Wang YM. Antarctic krill oil exhibited synergistic effects with nobiletin and theanine in ameliorating memory and cognitive deficiency in SAMP8 mice: Applying the perspective of the sea-land combination to retard brain aging. Front Aging Neurosci. 2022 Sep 16;14:964077. doi: 10.3389/fnagi.2022.964077. PMID: 36185487;PMCID: PMC9523088.
42440: Huang Y, Li X, Luo G, Wang J, Li R, Zhou C, Wan T, Yang F. Pyroptosis as a candidate therapeutic target for Alzheimer's disease. Front Aging Neurosci. 2022Sep 15;14:996646. doi: 10.3389/fnagi.2022.996646. PMID: 36185484; PMCID:PMC9520296.
43241: Kim HS, Shin SM, Kim S, Nam Y, Yoo A, Moon M. Relationship between adult subventricular neurogenesis and Alzheimer's disease: Pathologic roles and therapeutic implications. Front Aging Neurosci. 2022 Sep 14;14:1002281. doi:10.3389/fnagi.2022.1002281. PMID: 36185481; PMCID: PMC9518691.
44242: Wu L, Cao T, Li S, Yuan Y, Zhang W, Huang L, Cai C, Fan L, Li L, Wang J, Liu T, Wang J. Long-term gamma transcranial alternating current stimulation improves the memory function of mice with Alzheimer's disease. Front Aging Neurosci. 2022Sep 15;14:980636. doi: 10.3389/fnagi.2022.980636. PMID: 36185476; PMCID:
45143: Yang J, Wang Z, Fu Y, Xu J, Zhang Y, Qin W, Zhang Q. Prediction value of the genetic risk of type 2 diabetes on the amnestic mild cognitive impairment conversion to Alzheimer's disease. Front Aging Neurosci. 2022 Sep 15;14:964463.doi: 10.3389/fnagi.2022.964463. PMID: 36185474; PMCID: PMC9521369.
46544: Khodabakhsh P, Bazrgar M, Mohagheghi F, Parvardeh S, Ahmadiani A. MicroRNA-140-5p inhibitor attenuates memory impairment induced by amyloid-ß oligomer in vivo possibly through Pin1 regulation. CNS Neurosci Ther. 2022 Oct2. doi: 10.1111/cns.13980. Epub ahead of print. PMID: 36184817.
47645: Yuyama K, Sun H, Igarashi Y, Monde K, Hirase T, Nakayama M, Makino Y. Immuno-digital invasive cleavage assay for analyzing Alzheimer's amyloid ß-bound extracellular vesicles. Alzheimers Res Ther. 2022 Oct 3;14(1):140. doi:10.1186/s13195-022-01073-w. PMID: 36184615; PMCID: PMC9528138.
48246: Villain N, Planche V, Levy R. High-clearance anti-amyloid immunotherapies in Alzheimer's disease. Part 1: Meta-analysis and review of efficacy and safety data, and medico-economical aspects. Rev Neurol (Paris). 2022 Sep29:S0035-3787(22)00738-X. doi: 10.1016/j.neurol.2022.06.012. Epub ahead ofprint. PMID: 36184326.
49247: Aschenbrenner AJ, Li Y, Henson RL, Volluz K, Hassenstab J, Verghese P, West T, Meyer MR, Kirmess KM, Fagan AM, Xiong C, Holtzman D, Morris JC, Bateman RJ, Schindler SE. Comparison of plasma and CSF biomarkers in predicting cognitive decline. Ann Clin Transl Neurol. 2022 Oct 2. doi: 10.1002/acn3.51670. Epub aheadof print. PMID: 36183195.
50348: Jana A, Wang X, Leasure JW, Magana L, Wang L, Kim YM, Dodiya H, Toth PT, Sisodia SS, Rehman J. Increased Type I interferon signaling and brain endothelial barrier dysfunction in an experimental model of Alzheimer's disease. Sci Rep. 2022 Oct 1;12(1):16488. doi: 10.1038/s41598-022-20889-y. PMID:36182964; PMCID: PMC9526723.
51149: Lin L, Ni L, Wang X, Sheng C. Longitudinal cognitive change and duration of Alzheimer's disease stages in relation to cognitive reserve. Neuroscience. 2022 Sep 28:S0306-4522(22)00487-0. doi: 10.1016/j.neuroscience.2022.09.017. Epubahead of print. PMID: 36181989.
52550: Faridar A, Vasquez M, Thome AD, Yin Z, Xuan H, Wang JH, Wen S, Li X, Thonhoff JR, Zhao W, Zhao H, Beers DR, Wong STC, Masdeu JC, Appel SH. Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease. Acta Neuropathol Commun. 2022 Sep 30;10(1):144.doi: 10.1186/s40478-022-01447-z. PMID: 36180898; PMCID: PMC9524037.
53151: Mehla J, Deibel SH, Karem H, Hossain S, Lacoursiere SG, Sutherland RJ, Mohajerani MH, McDonald RJ. Dramatic impacts on brain pathology, anxiety, and cognitive function in the knock-in APP<sup>NL-G-F</sup> mouse model of Alzheimer disease following long-term voluntary exercise. Alzheimers Res Ther. 2022 Sep30;14(1):143. doi: 10.1186/s13195-022-01085-6. PMID: 36180883; PMCID:PMC9526288.
54252: Ma G, Zhang DF, Zou QC, Xie X, Xu L, Feng XL, Li X, Han JB, Yu D, Deng ZH, Qu W, Long J, Li MH, Yao YG, Zeng J. SARS-CoV-2 Spike protein S2 subunit modulates γ-secretase and enhances amyloid-β production in COVID-19 neuropathy. Cell Discov. 2022 Sep 30;8(1):99. doi: 10.1038/s41421-022-00458-3. PMID:36180433; PMCID: PMC9524330.
55653: Spatial-Temporal Patterns of β-Amyloid Accumulation: A Subtype and Stage Inference Model Analysis. Neurology. 2022 Sep 30:10.1212/WNL.0000000000201144.doi: 10.1212/WNL.0000000000201144. Epub ahead of print. Erratum for: Neurology.2022 Apr 26;98(17):e1692-e1703. PMID: 36180245.
56354: Karimi-Zandi L, Zahmatkesh M, Hassanzadeh G, Hosseinzadeh S. Increment of CSF fractalkine-positive microvesicles preceded the spatial memory impairment in amyloid beta neurotoxicity. Cytokine. 2022 Sep 27;160:156050. doi:10.1016/j.cyto.2022.156050. Epub ahead of print. PMID: 36179535.
57855: Sonar K, Mancera RL. Characterization of the Conformations of Amyloid Beta 42 in Solution That May Mediate Its Initial Hydrophobic Aggregation. J Phys Chem B. 2022 Sep 30. doi: 10.1021/acs.jpcb.2c04743. Epub ahead of print. PMID:36179370
58156: Kang CM, Bang JS, Park SY, Jung TW, Kim HC, Chung YH, Jeong JH. The Aqueous Extract of <i>Humulus japonicus</i> Ameliorates Cognitive Dysfunction in Alzheimer's Disease Models via Modulating the Cholinergic System. J Med Food. 2022 Sep 29. doi: 10.1089/jmf.2021.K.0197. Epub ahead of print. PMID: 36178947.
59257: Chen CH, Jong YJ, Chao YY, Wang CC, Chen YL. Fluorescent aptasensor based on conformational switch-induced hybridization for facile detection of β-amyloid oligomers. Anal Bioanal Chem. 2022 Sep 30. doi: 10.1007/s00216-022-04350-7. Epubahead of print. PMID: 36178490.
60358: Mandlik DS, Mandlik SK, S Arulmozhi. Therapeutic Implications of Glycogen Synthase Kinase-3β in Alzheimer's disease: A Novel Therapeutic Target. Int J Neurosci. 2022 Sep 30:1-27. doi: 10.1080/00207454.2022.2130297. Epub ahead ofprint. PMID: 36178363.
61159: Salkov VN, Voronkov DN, Khudoerkov RM. Rol' rtuti i mysh'yaka v etiologii I patogeneze boleznei Parkinsona i Al'tsgeimera [The role of mercury and arsenic in the etiology and pathogenesis of Parkinson's and Alzheimer's diseases]. ArkhPatol. 2022;84(5):59-64. Russian. doi: 10.17116/patol20228405159. PMID:36178224
62160: Hartz SM, Mozersky J, Schindler SE, Linnenbringer E, Wang J, Gordon BA, Raji CA, Moulder KL, West T, Benzinger TLS, Cruchaga C, Hassenstab JJ, Bierut LJ, Xiong C, Morris JC. A flexible modeling approach for biomarker-based computation of absolute risk of Alzheimer's disease dementia. Alzheimers Dement. 2022 Sep30. doi: 10.1002/alz.12781. Epub ahead of print. PMID: 36178120.
63161: Zhou R, Zhu L, Zeng Z, Luo R, Zhang J, Guo R, Zhang L, Zhang Q, Bi W. Targeted brain delivery of RVG29-modified rifampicin-loaded nanoparticles for Alzheimer's disease treatment and diagnosis. Bioeng Transl Med. 2022 Aug26;7(3):e10395. doi: 10.1002/btm2.10395. PMID: 36176608; PMCID: PMC9472014.
64262: Peven JC, Handen BL, Laymon CM, Fleming V, Piro-Gambetti B, Christian BT, Klunk W, Cohen AD, Okonkwo O, Hartley SL. Physical activity, memory function, and hippocampal volume in adults with Down syndrome. Front Integr Neurosci. 2022Sep 13;16:919711. doi: 10.3389/fnint.2022.919711. PMID: 36176326; PMCID:PMC9514120.
65263: Dafnis I, Mountaki C, Fanarioti E, Mastellos DC, Karvelas M, Karathanos VT, Tzinia A, Dermon CR, Chroni A. Temporal Pattern of Neuroinflammation Associated with a Low Glycemic Index Diet in the 5xFAD Mouse Model of Alzheimer's Disease. Mol Neurobiol. 2022 Sep 29. doi: 10.1007/s12035-022-03047-3. Epub ahead ofprint. PMID: 36175825.
66164: Lu J, Zhang S, Huang Y, Qian J, Tan B, Qian X, Zhuang J, Zou X, Li Y, Yan F. Periodontitis-related salivary microbiota aggravates Alzheimer's disease via gut-brain axis crosstalk. Gut Microbes. 2022 Jan-Dec;14(1):2126272. doi:10.1080/19490976.2022.2126272. PMID: 36175166.
67265: Wang X, Chen R, Hu J, Yuan W. An adjustable amyloid-β oligomers aptasensor based on the synergistic effect of self-enhanced metal-organic gel luminophore and triple-helix DNA system. Int J Biol Macromol. 2022 Sep 26;222(Pt A):794-802.doi: 10.1016/j.ijbiomac.2022.09.182. Epub ahead of print. PMID: 36174865.
68166: Grobbelaar LM, Kruger A, Venter C, Burger EM, Laubscher GJ, Maponga TG, Kotze MJ, Kwaan HC, Miller JB, Fulkerson D, Huff W, Chang E, Wiarda G, Bunch CM, Walsh MM, Raza S, Zamlut M, Moore HB, Moore EE, Neal MD, Kell DB, Pretorius E. Relative Hypercoagulopathy of the SARS-CoV-2 Beta and Delta Variants when Compared to the Less Severe Omicron Variants Is Related to TEG Parameters, the Extent of Fibrin Amyloid Microclots, and the Severity of Clinical Illness. Semin Thromb Hemost. 2022 Sep 29. doi: 10.1055/s-0042-1756306. Epub ahead of print. PMID: 36174604.
69167: Szunerits S, Abderrahmani A, Boukherroub R. Nanoparticles and Nanocolloidal Carbon: Will They Be the Next Antidiabetic Class That Targets Fibrillation and Aggregation of Human Islet Amyloid Polypeptide in Type 2 Diabetes? Acc Chem Res. 2022 Sep 29. doi: 10.1021/acs.accounts.2c00415. Epub ahead of print. PMID:36174237
70568: Chakravorty A, McCalpin SD, Sahoo BR, Ramamoorthy A, Brooks CL 3rd. Free Gangliosides Can Alter Amyloid-β Aggregation. J Phys Chem Lett. 2022 Sep29:9303-9308. doi: 10.1021/acs.jpclett.2c02362. Epub ahead of print. PMID:36174129
71569: Saha J, Bose P, Dhakal S, Ghosh P, Rangachari V. Ganglioside-Enriched Phospholipid Vesicles Induce Cooperative Aβ Oligomerization and Membrane Disruption. Biochemistry. 2022 Sep 29. doi: 10.1021/acs.biochem.2c00495. Epubahead of print. PMID: 36173882.
72370: Hong CG, Chen ML, Duan R, Wang X, Pang ZL, Ge LT, Lu M, Xie H, Liu ZZ. Transplantation of Nasal Olfactory Mucosa Mesenchymal Stem Cells Benefits Alzheimer's Disease. Mol Neurobiol. 2022 Sep 29. doi:10.1007/s12035-022-03044-6. Epub ahead of print. PMID: 36173534.
73571: Wu R, Ou X, Zhang L, Song X, Wang Z, Dong M, Liu L. Electric Field Effect on Inhibiting the Co-fibrillation of Amyloid Peptides by Modulating the Aggregation Pathway. Langmuir. 2022 Sep 29. doi: 10.1021/acs.langmuir.2c02055. Epub ahead ofprint. PMID: 36173231.
74372: Shademan B, Avci CB, Karamad V, Sogutlu F, Nourazarian A. MicroRNAs as a new target for Alzheimer's disease treatment. Microrna. 2022 Sep 28. doi:10.2174/2211536611666220928154015. Epub ahead of print. PMID: 36173083.
75173: Chakrovorty A, Bhattacharjee B, Saxena A, Samadder A, Nandi S. Current naturopathy to combat Alzheimer's disease. Curr Neuropharmacol. 2022 Sep 27.doi: 10.2174/1570159X20666220927121022. Epub ahead of print. PMID: 36173068.
76474: Li S, Wu L, Ma M, Yang L, Qin C. MicroRNA-668-3p regulates oxidative stress and cell damage induced by Aβ1-42 by targeting the <i>OXR1</i>/p53-p21 axis. AnnTransl Med. 2022 Sep;10(17):928. doi: 10.21037/atm-22-3598. PMID: 36172098;PMCID: PMC9511202.
77175: Zakharova NV, Bugrova AE, Indeykina MI, Fedorova YB, Kolykhalov IV, Gavrilova SI, Nikolaev EN, Kononikhin AS. Proteomic Markers and Early Prediction of Alzheimer's Disease. Biochemistry (Mosc). 2022 Aug;87(8):762-776. doi:10.1134/S0006297922080089. PMID: 36171657.
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2766and sorfra plaque formation in human hippocampal formation. Front AgingNeurosci. 2022 Aug 1;14:926904. doi: 10.3389/fnagi.2022.926904. PMID: 35978952;PMCID: PMC9376392.
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27808: Riboldi GM, Vialle RA, Navarro E, Udine E, de Paiva Lopes K, Humphrey J,Allan A, Parks M, Henderson B, Astudillo K, Argyrou C, Zhuang M, Sikder T, OriolNarcis J, Kumar SD, Janssen W, Sowa A, Comi GP, Di Fonzo A, Crary JF, Frucht SJ,
2781Allan A, Parks M, Henderson B, Astudillo K, Argyrou C, Zhuang M, Sikder T, OriolNarcis J, Kumar SD, Janssen W, Sowa A, Comi GP, Di Fonzo A, Crary JF, Frucht SJ,Raj T. Transcriptome deregulation of peripheral monocytes and whole blood in
2782Narcis J, Kumar SD, Janssen W, Sowa A, Comi GP, Di Fonzo A, Crary JF, Frucht SJ,Raj T. Transcriptome deregulation of peripheral monocytes and whole blood inGBA-related Parkinson's disease. Mol Neurodegener. 2022 Aug 17;17(1):52. doi:
2783Raj T. Transcriptome deregulation of peripheral monocytes and whole blood inGBA-related Parkinson's disease. Mol Neurodegener. 2022 Aug 17;17(1):52. doi:10.1186/s13024-022-00554-8. PMID: 35978378; PMCID: PMC9386994.
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27879: Singh D. Astrocytic and microglial cells as the modulators ofneuroinflammation in Alzheimer's disease. J Neuroinflammation. 2022 Aug17;19(1):206. doi: 10.1186/s12974-022-02565-0. PMID: 35978311; PMCID:
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279210: Sakamuri SSVP, Sure VN, Wang X, Bix G, Fonseca VA, Mostany R, Katakam PVG.Amyloid [Formula: see text] (1-42) peptide impairs mitochondrial respiration inprimary human brain microvascular endothelial cells: impact of dysglycemia and
2793Amyloid [Formula: see text] (1-42) peptide impairs mitochondrial respiration inprimary human brain microvascular endothelial cells: impact of dysglycemia andpre-senescence. Geroscience. 2022 Aug 17. doi: 10.1007/s11357-022-00644-x. Epub
2794primary human brain microvascular endothelial cells: impact of dysglycemia andpre-senescence. Geroscience. 2022 Aug 17. doi: 10.1007/s11357-022-00644-x. Epubahead of print. PMID: 35978067.
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280713: Xiang J, Xiang C, Zhou L, Sun M, Feng L, Liu C, Cai L, Gong P. RationalDesign, Synthesis of Fluorescence Probes for Quantitative Detection of Amyloid-βin Alzheimer's Disease Based on Rhodamine-Metal Complex. Anal Chem. 2022 Aug
2808Design, Synthesis of Fluorescence Probes for Quantitative Detection of Amyloid-βin Alzheimer's Disease Based on Rhodamine-Metal Complex. Anal Chem. 2022 Aug30;94(34):11791-11797. doi: 10.1021/acs.analchem.2c01911. Epub 2022 Aug 17.
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281314: Fidan GS, Parlar S, Tarikogullari AH, Alptuzun V, Alpan AS. Design,synthesis, acetylcholinesterase, butyrylcholinesterase, and amyloid-βaggregation inhibition studies of substituted 4,4'-diimine/4,4'-diazobiphenyl
2814synthesis, acetylcholinesterase, butyrylcholinesterase, and amyloid-βaggregation inhibition studies of substituted 4,4'-diimine/4,4'-diazobiphenylderivatives. Arch Pharm (Weinheim). 2022 Aug 17:e2200152. doi:
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281915: Rubin R. Much Anticipated Alzheimer Disease Prevention Trial Finds NoClinical Benefit From Drug Targeting Amyloid; Highlights Need to Consider OtherApproaches. JAMA. 2022 Sep 13;328(10):907-910. doi: 10.1001/jama.2022.11490.
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282416: Studart-Neto A, Coutinho AM. From clinical phenotype to proteinopathy:molecular neuroimaging in neurodegenerative dementias. Arq Neuropsiquiatr. 2022May;80(5 Suppl 1):24-35. doi: 10.1590/0004-282X-ANP-2022-S138. PMID: 35976328.
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282817: Brucki SMD, César-Freitas KG, Spera RR, Borges CR, Smid J. Are we ready touse anti-amyloid therapy in Alzheimer's disease? Arq Neuropsiquiatr. 2022May;80(5 Suppl 1):15-23. doi: 10.1590/0004-282X-ANP-2022-S117. PMID: 35976307.
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283218: Chang HW, Ma HI, Wu YS, Lee MC, Chung-Yueh Yuan E, Huang SJ, Cheng YS, WuMH, Tu LH, Chan JCC. Site specific NMR characterization of abeta-40 oligomerscross seeded by abeta-42 oligomers. Chem Sci. 2022 Jun 22;13(29):8526-8535. doi:
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283719: Lam S, Hérard AS, Boluda S, Petit F, Eddarkaoui S, Cambon K; BrainbankNeuro-CEB Neuropathology Network, Picq JL, Buée L, Duyckaerts C, Haïk S, DhenainM. Pathological changes induced by Alzheimer's brain inoculation in amyloid-beta
2838Neuro-CEB Neuropathology Network, Picq JL, Buée L, Duyckaerts C, Haïk S, DhenainM. Pathological changes induced by Alzheimer's brain inoculation in amyloid-betaplaque-bearing mice. Acta Neuropathol Commun. 2022 Aug 16;10(1):112. doi:
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2844Y, Pakkenberg B, Woldbye DPD, Dmytriyeva O, Pankratova S. Modeling the earlystages of Alzheimer's disease by administering intracerebroventricularinjections of human native Aβ oligomers to rats. Acta Neuropathol Commun. 2022
2845stages of Alzheimer's disease by administering intracerebroventricularinjections of human native Aβ oligomers to rats. Acta Neuropathol Commun. 2022Aug 16;10(1):113. doi: 10.1186/s40478-022-01417-5. PMID: 35974377; PMCID:
2846injections of human native Aβ oligomers to rats. Acta Neuropathol Commun. 2022Aug 16;10(1):113. doi: 10.1186/s40478-022-01417-5. PMID: 35974377; PMCID:PMC9380371.
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285021: He CY, Tian DY, Chen SH, Jin WS, Cheng Y, Xin JY, Li WW, Zeng GH, Tan CR,Jian JM, Fan DY, Ren JR, Liu YH, Wang YJ, Zeng F. Elevated Levels of Naturally-Occurring Autoantibodies Against the Extracellular Domain of p75NTR Aggravate
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286123: Oberstein TJ, Schmidt MA, Florvaag A, Haas AL, Siegmann EM, Olm P, Utz J,Spitzer P, Doerfler A, Lewczuk P, Kornhuber J, Maler JM. Amyloid-β levels andcognitive trajectories in non-demented pTau181-positive subjects without
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286724: Nicastro LK, de Anda J, Jain N, Grando KCM, Miller AL, Bessho S, Gallucci S,Wong GCL, Tükel Ç. Assembly of ordered DNA-curli fibril complexes duringSalmonella biofilm formation correlates with strengths of the type I interferon
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288127: Gopalakrishna R, Lin CY, Oh A, Le C, Yang S, Hicks A, Kindy MS, Mack WJ,Bhat NR. cAMP-induced decrease in cell-surface laminin receptor and cellularprion protein attenuates amyloid-β uptake and amyloid-β-induced neuronal cell
2882Bhat NR. cAMP-induced decrease in cell-surface laminin receptor and cellularprion protein attenuates amyloid-β uptake and amyloid-β-induced neuronal celldeath. FEBS Lett. 2022 Aug 6. doi: 10.1002/1873-3468.14467. Epub ahead of print.
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288728: Rafii MS, Sperling RA, Donohue MC, Zhou J, Roberts C, Irizarry MC, Dhadda S,Sethuraman G, Kramer LD, Swanson CJ, Li D, Krause S, Rissman RA, Walter S, RamanR, Johnson KA, Aisen PS. The AHEAD 3-45 Study: Design of a prevention trial for
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2894Chatterjee U, Kronqvist N, Barajas-Ledesma E, Kumar R, Chen G, Strömberg R,Abelein A, Langton M, Landreh M, Barth A, Holland C, Johansson J, Rising A.Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and
2895Abelein A, Langton M, Landreh M, Barth A, Holland C, Johansson J, Rising A.Spidroin N-terminal domain forms amyloid-like fibril based hydrogels andprovides a protein immobilization platform. Nat Commun. 2022 Aug 15;13(1):4695.
2896Spidroin N-terminal domain forms amyloid-like fibril based hydrogels andprovides a protein immobilization platform. Nat Commun. 2022 Aug 15;13(1):4695.doi: 10.1038/s41467-022-32093-7. PMID: 35970823; PMCID: PMC9378615.
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290030: Dumurgier J, Sabia S, Zetterberg H, Teunissen CE, Hanseeuw B, Orellana A,Schraen S, Gabelle A, Boada M, Lebouvier T, Willemse EAJ, Cognat E, Ruiz A,Hourregue C, Lilamand M, Bouaziz-Amar E, Laplanche JL, Lehmann S, Pasquier F,
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290931: Figueira AJ, Moreira GG, Saavedra J, Cardoso I, Gomes CM. Tetramerization ofthe S100B Chaperone Spawns a Ca<sup>2+</sup> Independent Regulatory Surface thatEnhances Anti-aggregation Activity and Client Specificity. J Mol Biol. 2022 Oct
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291532: Gao X, Wang Z, Xiong L, Wu F, Gan X, Liu J, Huang X, Liu J, Tang L, Li Y,Huang J, Huang Y, Li W, Zeng H, Ban Y, Chen T, He S, Lin A, Han F, Guo X, Yu Q,Shu W, Zhang B, Zou R, Zhou Y, Chen Y, Tian H, Wei W, Zhang Z, Wei C, Wei Y, Liu
2916Huang J, Huang Y, Li W, Zeng H, Ban Y, Chen T, He S, Lin A, Han F, Guo X, Yu Q,Shu W, Zhang B, Zou R, Zhou Y, Chen Y, Tian H, Wei W, Zhang Z, Wei C, Wei Y, LiuH, Yao H, Chen Q, Zou Z. The bs-YHEDA peptide protects the brains of senile mice
2917Shu W, Zhang B, Zou R, Zhou Y, Chen Y, Tian H, Wei W, Zhang Z, Wei C, Wei Y, LiuH, Yao H, Chen Q, Zou Z. The bs-YHEDA peptide protects the brains of senile miceand thus recovers intelligence by reducing iron and free radicals. Free Radic
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2919and thus recovers intelligence by reducing iron and free radicals. Free RadicBiol Med. 2022 Sep;190:216-225. doi: 10.1016/j.freeradbiomed.2022.08.014. Epub2022 Aug 13. PMID: 35970250.
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292834: Pham NTT, Graff-Radford J, Machulda MM, Spychalla AJ, Schwarz CG, Senjem ML,Lowe VJ, Vemuri P, Kantarci K, Knopman DS, Petersen RC, Jack CR, Josephs KA,Whitwell JL. Regional white matter hyperintensities in posterior cortical
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293435: Murray KA, Hu CJ, Griner SL, Pan H, Bowler JT, Abskharon R, Rosenberg GM,Cheng X, Seidler PM, Eisenberg DS. De novo designed protein inhibitors ofamyloid aggregation and seeding. Proc Natl Acad Sci U S A. 2022 Aug
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294036: Nakaie M, Katayama F, Nakagaki T, Yoshida S, Kawasaki M, Nishi K, Ogawa K,Toriba A, Nishida N, Nakayama M, Fuchigami T. Synthesis and BiologicalEvaluation of Novel 2-(Benzofuran-2-yl)-chromone Derivatives for In Vivo Imaging
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2947CT. Adult-Onset Deficiency of Mitochondrial Complex III in a Mouse Model ofAlzheimer's Disease Decreases Amyloid Beta Plaque Formation. Mol Neurobiol. 2022Oct;59(10):6552-6566. doi: 10.1007/s12035-022-02992-3. Epub 2022 Aug 15. PMID:
2948Alzheimer's Disease Decreases Amyloid Beta Plaque Formation. Mol Neurobiol. 2022Oct;59(10):6552-6566. doi: 10.1007/s12035-022-02992-3. Epub 2022 Aug 15. PMID:35969330; PMCID: PMC9464722.
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295238: Cosarderelioglu C, Nidadavolu LS, George CJ, Marx-Rattner R, Powell L, XueQL, Tian J, Oh ES, Ferrucci L, Dincer P, Bennett DA, Walston JD, Abadir PM.Angiotensin receptor blocker use is associated with upregulation of the memory-
2953QL, Tian J, Oh ES, Ferrucci L, Dincer P, Bennett DA, Walston JD, Abadir PM.Angiotensin receptor blocker use is associated with upregulation of the memory-protective angiotensin type 4 receptor (AT<sub>4</sub>R) in the postmortem
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3393118: Eid A, Mhatre-Winters I, Sammoura FM, Edler MK, von Stein R, Hossain MM,Han Y, Lisci M, Carney K, Konsolaki M, Hart RP, Bennett JW, Richardson JR.Effects of DDT on Amyloid Precursor Protein Levels and Amyloid Beta Pathology:
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3410121: Jangir N, Bangrawa S, Yadav T, Malik S, Alamri AS, Galanakis CM, Singh M,Yadav JK. Isolation and characterization of amyloid-like protein aggregates fromsoya beans and the effect of low pH and heat treatment on their stability. J
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3431125: Bell R, Thrush RJ, Castellana-Cruz M, Oeller M, Staats R, Nene A, FlagmeierP, Xu CK, Satapathy S, Galvagnion C, Wilson MR, Dobson CM, Kumita JR,Vendruscolo M. N-Terminal Acetylation of α-Synuclein Slows down Its Aggregation
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3438126: Werny L, Grogro A, Bickenbach K, Bülck C, Armbrust F, Koudelka T, Pathak K,Scharfenberg F, Sammel M, Sheikhouny F, Tholey A, Linder S, Becker-Pauly C.MT1-MMP and ADAM10/17 exhibit a remarkable overlap of shedding properties. FEBS
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3464131: Piazza F, Caminiti SP, Zedde M, Presotto L, DiFrancesco JC, Pascarella R,Giossi A, Sessa M, Poli L, Basso G, Perani D. Association of MicroglialActivation With Spontaneous ARIA-E and Cerebrospinal Fluid Levels of Anti-A
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3475133: Wang J, Qie J, Zhu D, Zhang X, Zhang Q, Xu Y, Wang Y, Mi K, Pei Y, Liu Y,Ji G, Liu X. The landscape in the gut microbiome of long-lived families revealsnew insights on longevity and aging - relevant neural and immune function. Gut
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3477new insights on longevity and aging - relevant neural and immune function. GutMicrobes. 2022 Jan-Dec;14(1):2107288. doi: 10.1080/19490976.2022.2107288. PMID:35939616; PMCID: PMC9361766.
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3481134: Rofo F, Meier SR, Metzendorf NG, Morrison JI, Petrovic A, Syvänen S, SehlinD, Hultqvist G. A Brain-Targeting Bispecific-Multivalent Antibody Clears SolubleAmyloid-Beta Aggregates in Alzheimer's Disease Mice. Neurotherapeutics. 2022 Aug
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3486135: Xiong J, Lu DL, Chen BQ, Liu TY, Wang ZX. Dimethyl Itaconate ReducesCognitive Impairment and Neuroinflammation in APPswe/PS1ΔE9 Transgenic MouseModel of Alzheimer's Disease. Neuromolecular Med. 2022 Aug 8. doi:
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3491136: Eyileten C, Wicik Z, Simões SN, Martins-Jr DC, Klos K, Wlodarczyk W,Assinger A, Soldacki D, Chcialowski A, Siller-Matula JM, Postula M. Thrombosis-related circulating miR-16-5p is associated with disease severity in patients
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3497137: El-Nashar HAS, Adel M, El-Shazly M, Yahia IS, El Sheshtawy HS, Almalki AA,Ibrahim N. Chemical Composition, Antiaging Activities and Molecular DockingStudies of Essential Oils from Acca sellowiana (Feijoa). Chem Biodivers. 2022
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3559149: Mehdipour M, Emamghoreishi M, Farrokhi MR, Amirinezhadfard E, Keshavarz M.The Effect of Spironolactone on β-amyloid-Induced Memory Impairment in MaleRats: The Role of Microglial Inhibition. Adv Pharm Bull. 2022 May;12(3):623-631.
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3564150: Schäffler M, Khaled M, Strodel B. ATRANET - Automated generation oftransition networks for the structural characterization of intrinsicallydisordered proteins. Methods. 2022 Oct;206:18-26. doi:
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3569151: Zhou Y, Li ZX, Liu YT, Xu ZC, Hu Y, Lv W, Yang ZY, Sheng YM, Liu S.N-linoleyltyrosine protects neurons against Aβ<sub>1-40</sub>-induced celltoxicity via autophagy involving the CB<sub>2</sub>/AMPK/mTOR/ULK1 pathway.
3570N-linoleyltyrosine protects neurons against Aβ<sub>1-40</sub>-induced celltoxicity via autophagy involving the CB<sub>2</sub>/AMPK/mTOR/ULK1 pathway.Brain Res Bull. 2022 Oct 1;188:203-213. doi: 10.1016/j.brainresbull.2022.08.002.
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3609AE, Fernández MV, Day GS, McDade E, Bateman RJ, Karch CM, Llibre-Guerra JJ;Dominantly Inherited Alzheimer Network. Discovery and validation of dominantlyinherited Alzheimer's disease mutations in populations from Latin America.
3610Dominantly Inherited Alzheimer Network. Discovery and validation of dominantlyinherited Alzheimer's disease mutations in populations from Latin America.Alzheimers Res Ther. 2022 Aug 5;14(1):108. doi: 10.1186/s13195-022-01052-1.
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3645164: Khan AN, Nabi F, Ajmal MR, Ali SM, Almutairi FM, Alalawy AI, Khan RH.Moxifloxacin Disrupts and Attenuates Aβ42 Fibril and Oligomer Formation:Plausibly Repositioning an Antibiotic as Therapeutic against Alzheimer's
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3651165: Uchino A, Irie Y, Tsukano C, Kawase T, Hirose K, Kageyama Y, Tooyama I,Yanagita RC, Irie K. Synthesis and Characterization of Propeller- and Parallel-Type Full-Length Amyloid β40 Trimer Models. ACS Chem Neurosci. 2022 Aug
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3695173: Haddad HW, Malone GW, Comardelle NJ, Degueure AE, Kaye AM, Kaye AD.Aducanumab, a Novel Anti-Amyloid Monoclonal Antibody, for the Treatment ofAlzheimer's Disease: A Comprehensive Review. Health Psychol Res. 2022 Jan
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3727179: Beura SK, Dhapola R, Panigrahi AR, Yadav P, Reddy DH, Singh SK. Redefiningoxidative stress in Alzheimer's disease: Targeting platelet reactive oxygenspecies for novel therapeutic options. Life Sci. 2022 Oct 1;306:120855. doi:
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