ABC
1Main
2BrandOnpattro
3Genericpatisiran
4IndicationATTR Amyloidosis. Neuropathy & Cardiomyopathy.
5Clinical Trials
6Phase III "APOLLO-B" n=360 ATTR with cardiomyopathy
76MW PE met at 12 months: +14.7m, p=0.0162
8'-8.15 for patisiran, -21.345 for placebo
9Initially presented at ISA, press release 8/2022; HFSA 10/2022
100.3mg/kg IV q3w
11MACE HR=0.839 p=NS