ABC
1Main
2Brand NameBMS-790052
3IndicationHCV
4MechanismNS5A inhibitor
5Clinical Trials
6Phase IIa n=48 tx-naïve g1 HCV reported at EASL 2010
710mg QD/60mg QD RVR of 92%/83%. cEVR 83%/83% (42% placebo). eRVR 83%/75% (8% placebo).
8PROVE RVR/EVR of 69-81% and 68%-80%.
9
10Single-dose in HCV
111.8log, 3.2log and 3.3log up to 100mg