A | B | C | |
---|---|---|---|
1 | Main | ||
2 | Brand Name | ||
3 | Generic Name | ipilimumab | |
4 | Mechanism | CTLA4 antibody | |
5 | Indication | 2L melanoma | |
6 | Economics | MEDX | |
7 | Clinical Trials | ||
8 | Phase III | ||
9 | |||
10 | |||
11 | Phase III comparing gp100, ipi+gp100 vs ipi alone | ||
12 | Ipi-alone and Ipi+gp100 both S.S. vs. gp100 (HR=0.66, 0.68). 10.0, 10.1 and 6.4 months for Ipi, ipi+gp100 and gp100. | ||
13 | |||
14 | Phase I/II mixed leukemias/lymphomas n=17 single-dose, dose-escalation | ||
15 | 1 NHL patient had ongoing CR, 1 MCL with PR | ||
16 | |||
17 | Phase I/II relapsed/refractory follicular lymphoma n=12 | ||
18 | 1 patient with a PR |